国家基本药物制度研究主题的可视化分析

Visualization Studies of Research Subjects of China's National Essential Drug System

目的分析我国国家基本药物制度研究的研究主题,为今后国家基本药物制度的不断完善提供参考。方法于2017-02-28,计算机检索中国生物医学文献数据库(CBMdisc)、中国知网、万方数据知识服务平台中与国家基本药物制度有关的文献,均从建库检索至2016-12-31。根据美国国立医学图书馆编制的《医学主题词表(Me SH)》中译本和《中国中医药学主题词表》对纳入文献的主题词进行标化。采用书目信息共现挖掘系统(BICOMS)对主题词信息进行抽取和整理,并生成共现矩阵;采用Ucinet 6.0软件中的Net Draw绘制主题词的社会网络分析图;采用g CLUTO 2.0软件对主要主题词进行聚类分析。结果共获得国家基本药物制度相关文献2 096篇,具有实质意义主题词1 588个,核心主题词为国家基本药物制度、国家基本药物、基层医疗机构。聚类分析共获得7个主题,分别为:主题1,国家基本药物制度实施存在的问题及对策研究;主题2,国家基本药物制度政策建议/评价/实施与制度建设/改革/落实;主题3,社区卫生服务机构医务人员对国家基本药物制度认知和满意度调查;主题4,国家基本药物制度补偿方式/机制/标准/政策及其效果分析/评价以及药品的零差率补偿/政策/销售;主题5,国家基本药物制度对基层医疗机构抗菌药物合理用药的影响因素研究;主题6,国家基本药物制度对基本药物遴选和用药频度的影响;主题7,医疗卫生机构国家基本药物的可获得性及实施效果/策略/模式研究。结论目前关于国家基本药物制度的研究主要集中在补偿、效果分析及实施效果等方面,今后的研究应关注国家基本药物制度与医疗保险及其实施评价指标的建立。

Objective To analyze the research topics of China＇s national essential drug system（ NEDS）,in order to provide a reference for its development in the future. Methods On February 28 th,2017, we searched the databases of CBMdisc,CNKI,WANFANG DATA for articles that studied China＇s NEDS as of December 31 st,2016. The subject headings of the included articles were standardized based on the Chinese version of Medical Subject Headings（ Me SH） developed by the National Library of Medicine and Chinese Traditional Medicine and Materia Medica Subject Headings. Bibliographic Item Co-occurrence Mining System（ BICOMS） was used to extract and summarize the data of subject headings and produced a co-occurrence matrix. Net Draw of Ucinet 6. 0 was employed to draw the social network diagram of the subject headings. And cluster analysis of the subject headings was performed by g CLUTO 2. 0. Results A total of 2 096 studies involving 1 588 medical subject headings with substantial meanings were included. The three major subject headings were NEDS,national essential medicine,and grassroots medical institutions. The subject headings were divided into 7 research topics： 1 Challenges for the implementation of China＇s NEDS and corresponding countermeasures; 2 Suggestions for/assessment/reform of the implementation of China＇ s NEDS,and implementation and development of China＇s NEDS; 3 Surveys about the awareness of China＇s NEDS and satisfaction with the implementation of China＇ s NEDS in primary care providers; 4 Analyses of reimbursement ways/mechanism/standard/policy and effect about the implementation of China＇ s NEDS,and the compensation/policy related to the zero-profit sale of drugs; 5 Effect of the implementation of China＇ s NEDS on the reasonable use of antimicrobial agents in grassroots medical institutions; 6 Influence of NEDS on use frequency and selection of essential drugs; 7 Availability and implementation effect/implementation strategy/implementation model of China＇s NEDS. Conclusion The studies of China＇s NEDS focus on the aspects of compensation and effectiveness analysis of implementation. Future research should focus on the relationship between China＇ s NEDS and medical insurance,and the development of markers for the assessment of the implementation of China＇s NEDS.