幽门螺杆菌根除后继发难辨梭状芽孢杆菌感染一例报道并文献复习

Clostridium Difficile Infection Associated with Helicobacter Pylori Eradication:a Case Report and Literature Review

难辨梭状芽孢杆菌感染是幽门螺杆菌根除后的一种严重并发症,主要临床表现为大便性状、次数的改变,严重时可发展为伪膜性肠炎,但目前许多医生对此并不十分了解。本文报道了1例幽门螺杆菌根除后继发难辨梭状芽孢杆菌感染病例,并通过文献复习探讨幽门螺杆菌根除之后继发难辨梭状芽孢杆菌感染的临床表现和可能的发病机制,以提高临床医生对此病的警惕性。

Clostridium difficile infection （CDI） is one serious complication associated with Helicobacter pylori eradication clinically characterized by changes in stool frequency and consistency and even pseudomembranous colitis when it is severe. However, this is not being well understood by many doctors. We reported a case of secondary CDI following the Helicobacter pylori eradication therapy, and reviewed some articles in which the manifestations and possible mechanism of CDI secondary to the Helicobacter pylori eradication therapy were reported, in order to raise doctors＇ vigilance to this disease.