血细胞参数RPR对中青年男性非酒精性脂肪肝的预测价值

Blood Cell Parameters of RPR Value for the Forecast of Young and Middle-aged Male Nonalcoholic Fatty Liver Disease

目的血细胞参数RPR在中青年男性非酒精性脂肪肝(NAFLD)临床诊断中的预测价值。方法回顾性收集126例临床明确诊断为NAFLD的初发患者的几项临床检验指标,同时选取120例正常体检人群作为对照组。结果与正常体检组相比,NAFLD患者组的血细胞参数RPR为0.0749±0.0190,显著高于对照组的0.0506±0.0094,相比较差异有统计学意义(P<0.05);ROC曲线下面积为0.897,最佳诊断界值为0.05576,此时灵敏度为87.3%,特异性为74.56%,约登指数为0.6186,与临床诊断的正确率为82.52%。结论 NAFLD患者的血细胞参数RPR明显高于正常人,对中青年男性发生NAFLD有一定的预测价值。

Objective To explore the value of blood cell parameters of RPR in young and middle-aged male nonalcoholic fatty liver disease （NAFLD） predictive value in clinical diagnosis. Methods 126 cases of clinical diagnosis for patients with NAFLD of incipient several measures of clinical examination were collected, and at the same time 120 cases of normal physical examination population were collected as control group. Results Compared with control group, blood parameters of RPR average in patients with NAFLD was 0.0749 ±0.019, which was significantly higher than 0.0506 ± 0.0094 in the control group （P 〈 0.05）. Area under the ROC curve was 0.897, the best diagnostic value was 0.05576, the sensitivity was 87.3%, specificity was 74.56%, about an index was 0.6186, and clinical diagnostic accuracy was 82.52%. Conclusion RPR in patients with NAFLD was obviously higher than that of normal people. In young and middle-aged male, NAFLD have predictive value.