高通量血液透析联合左卡尼汀对维持性血液透析患者营养状况和生存质量的影响研究

Effect of high-flux hemodialysis and levocarnitine on nutritional status and survival quality in patients with maintenance hemodialysis

目的探讨高通量血液透析(HFHD)联合左卡尼汀对维持性血液透析(MHD)患者营养状况和生存质量的影响。方法选择我院收治的MHD患者90例,根据随机数表法分为A、B、C 3组,各30例。A组采用低通量血液透析(LFHD)治疗,B组采用HFHD治疗,C组采用HFHD+左卡尼汀治疗。比较3组营养状况与生存质量。结果治疗后C组生存质量评分、营养指标水平均显著升高,且高于A、B 2组,差异有统计学意义(P<0.05)。结论 MHD患者采用HFHD联合左卡尼汀治疗更有利于改善患者的炎症状态及营养状况,从而提高患者的生存质量。

Objective To investigate the effect of high-flux hemodialysis（HFMD）and levocarnitine on nutritional status and survival quality in patients with maintenance hemodialysis（MHD）.Methods 90 MHD patients in our hospital were divided into A,B,C group by random number table,30 cases in each group. A group was given low-flux hemodialysis（LFMD）,B group was given HFMD,C group was given HFMD and levocarnitine.The nutritional status and survival quality were compared among the three groups.Results After treatment,the score of survival quality,the level of nutritional index in C group significantly increased,which was higher than that in A,B group,and there was statistical difference（P0.05）.Conclusion HFMD and levocarnitine in treatment of MHD can improve inflammatory state and nutritional status,thus increasing survival quality of patients.