血栓通注射液对缺血性眼底病疗效及血流动力学的影响

Effects of Xueshuantong Injection and its influence on hemodynamics in patients with ischemic fundus disease

目的观察分析血栓通注射液治疗对缺血性眼底病患者疗效及血流动力学的影响。方法收集80例缺血性眼底病患者作为研究对象,分为两组,每组40例。对照组给予常规治疗,而观察组在对照组基础上给予血栓通注射液治疗。比较两组患者临床疗效、血液流变学指标及眼动脉血流速度。结果疗效评价显示,观察组治疗总有效率明显高于对照组,差异有统计学意义(P<0.05)。血流动力学指标方面,观察组治疗后全血黏度、血浆黏度、血细胞比容明显低于对照组,眼动脉收缩期峰值血流速度、舒张末期血流速度、平均血流速度均高于对照组,组间比较差异均有统计学意义(P<0.05)。结论血栓通注射液在缺血性眼底病患者中应用效果良好,治疗有效率高,而且能够明显改善血流动力学指标。

Objective To observe and analyze the effects of Xueshuantong Injection and its influence on hemodynamics in the patients with ischemic fundus disease.Methods Eithy patients with ischemic fundus disease were collected as the research subjects and divided into two groups,40 cases in each group.Then the control group was given the conventional treatment,while on this basis the observation group was given Xueshuantong Injection.The curative efficacy,hemorheology indices and blood flow velocity of ophthalmic arteries were compared between the two groups.Results The therapeutic efficacy evaluation showed that the total effective rate in the observation group was higher than that in the control group,the difference was statistically significant（P〈0.05）.In the aspects of hemodynamic indices,the whole blood viscosity,plasma viscosity,hematocrit after treatment in the observation group were significantly lower than those in the control group,while the peak systolic blood flow velocity,end diastolic velocity and average blood velocity of ophthalmic arteries in the observation group were higher than those in the control group,the differences were statistically significant（P〈0.05）.Conclusion Xueshuantong Injection has better effect with a high effective rate for treating ischemic fundus disease,moreover can significantly improve hemodynamic indices.