心康方治疗慢性心力衰竭的疗效研究

Clinical Effect Observation of Treatment of Xinkang Decoction in Patients with Chronic Heart Failure

目的观察心康方治疗慢性心力衰竭的临床疗效,从而探讨从肺论治慢性心力衰竭。方法将120例慢性心力衰竭患者随机分为对照组59例和治疗组61例。对照组采用常规西药抗心力衰竭治疗,治疗组在常规西药抗心力衰竭治疗的基础上加用心康方,两组疗程均为12周。治疗前后检测血浆脑钠肽(BNP)水平,测量左室射血分数(LVEF)、左室舒张末期内径(LVEDd),并观察临床疗效。结果治疗组在改善心功能分级以及降低脑钠肽水平、提高射血分数等方面均优于对照组(P<0.05)。结论加用中药心康方治疗慢性心力衰竭能够更好地缓解心衰临床症状,进一步提高左心室射血分数并降低血浆BNP水平,从肺论治慢性心力衰竭疗效确切。

Objective To observe the clinical efficacy of Xinkang Decoction in patients with chronic heart failure （CH F ） , and to explore the clinical efficacy of treatment by regulating Lung. Methods 120 cases of patients with chronic heart failure were randomly divided into two groups, The control group （n = 59） received conventional treatments. Besides the conventional treatments, the treatment group members were given Xinkang Decoction. The course of treatment was 12 weeks. These indicators were observed before and after the treatment including the plasma BNP level, left ventricular ejection fraction （LVEF） , left ventricular end diastolic diameter （LVEDd） , and the score of clinical therapeutic effect. Results The improvement of cardiac function classification, the level of brain natriuretic peptide and ejection fraction in treatment group were better than those of control group （ P 〈0.05）. Conclusion Xinkang Decoction in the treatment of congestive heart failure can better relieve heart failure clinical symptoms, improve left ventricular ejection fraction and reduce the levels of plasma BNP. Therefore, treatment by regulating Lung can significantly improve the clinical efficacy in patients with CHF.