腹水浓缩回输联合复方丹参注射液腹腔内注射治疗肝硬化难治性腹水临床观察

Treating refractory cirrhosis ascites with ascites concentration retransformation united with salvia miltiorrhiza parenteral solution intraperitoneal injection

目的:探究腹水浓缩回输联合丹参注射液腹腔内注射治疗肝硬化难治性腹水的临床疗效。方法:选取肝硬化难治性腹水患者60例,随机数字表法分为对照组和研究组各30例,对照组接受腹水超滤浓缩腹腔内回输治疗,研究组在对照组基础上增加丹参注射液腹腔内注射治疗。监测并比较两组患者治疗前后血清、腹水蛋白含量和肝肾功能,以及两组患者的治疗效果。结果:研究组患者的治疗总有效率是90.0%,对照组患者的治疗总有效率是53.3%,两组比较差异具有统计学意义(P<0.05)。经过治疗后所有患者的腹水总蛋白、腹水白蛋白、血清总蛋白、血清白蛋白水平均有所改善,且研究组患者改善程度明显优于对照组患者,二者比较差异具有统计学意义(P<0.05)。结论:采取腹水浓缩回输结合丹参注射液腹腔内注射的方法治疗肝硬化难治性腹水具有显著的临床疗效,且副作用小。

Objective： To investigate the clinical efficacy of intraperitoneal injection of ascites combined with salvia miltiorrhiza injection in the treatment of refractory ascites due to liver cirrhosis. Methods ：Sixty patients with refractory ascites admitted to our hospital were divided into control group and study group, 30 cases in each group. The control group received ascites ultrafiltration concentration intraperitoneal return treatment, the study group in the treatment group based on the increase in salvia injection intraperitoneal injection therapy. To monitor and com-pare the serum and ascites protein content and liver and kidney function of the two groups, and clinical efficacy of patients in both two groups. Results：The clinical effective rate of study group was 90. 0% , the control group was 53. 3% , there was statistically significance （P〈0.05）. After treatment, levels of total protein, ascites albumin, serum total protein and serum albumin were improved in the two groups, and the improvement degree of the study group was significantly better than those in the control group （P〈0.05）. Conclusion： Abdominal ascites combined with salvia miltiorrhiza injection intraperitoneal injection for the treatment of cirrhosis refractory ascites clinical effect is significant, side effects.