期刊文献+

儿童重症细菌感染抗生素降阶梯治疗中血清降钙素原的指导价值 被引量:2

下载PDF
导出
摘要 目的:探讨儿童重症细菌感染抗生素降阶梯治疗中血清降钙素原(PCT)的指导价值。方法:选取我院2014年5月-2017年2月收治的150例儿童重症细菌感染患儿,采取随机数字表将其分成两组,每组75例。观察组在血清PCT指导下进行抗生素降阶梯治疗,对照组经验性使用抗生素,比较两组治疗前、后血清PCT水平、患儿病死率、住院时间及住院费用。结果:两组治疗3d、5d血清PCT水平逐渐下降,且均明显低于治疗前(P<0.01),观察组治疗3d、5d血清PCT水平明显低于对照组同时点(P<0.01)。观察组患儿死亡率显著低于对照组(P<0.05),观察组患儿住院时间、住院费用均明显低于对照组(P<0.01)。结论:PCT指导儿童重症细菌感染抗生素降阶梯治疗可加快病情缓解,降低病死率,缩短住院时间,减少住院费用。
出处 《医学理论与实践》 2017年第19期2891-2893,共3页 The Journal of Medical Theory and Practice
  • 相关文献

参考文献6

二级参考文献78

  • 1Indino P, Lemarchand P, Bady P, et al. Prospective study on procalci- tonin and other systemic infection markers in patients with leukocytosis [J]. Int J Infect Dis,2008,12(3) :319-324.
  • 2Becker KL, Snider R, Nylen ES. Procalcitonin in sepsis and systemic inflammation:a harmful biomarker and a therapeutic target [ J ]. Br J Pharmaeo1,2010,159 ( 2 ) :253-264.
  • 3Crisafulli E,Menéndez R,Huerta A,et al.Systemic inflammatory pattern of patients with community-acquired pneumonia with and without COPD[J].Chest,2013,143(4):1009-1017.
  • 4Chiesa C,Natale F,Pascone R,et al.C reactive protein and procalcitonin:reference intervals for preterm and term newborns during the early neonatal period[J].Clin Chim Acta,2011,412(11-12):1053-1059.
  • 5Soler N,Esperatti M,Ewig S,et al.Sputum purulence-guided antibiotic use in hospitalised patients with exacerbations of COPD[J].Eur Respir J,2012,40(6):1344-1353.
  • 6Das RR,Singh M,Shafiq N.Short-term therapeutic role of zinc in children<5years of age hospitalised for severe acute lower respiratory tract infection[J].Paediatr Respir Rev,2012,13(3):184-191.
  • 7Ageno W,Spyropoulos AC,Turpie AG.Role of new anticoagulants for the prevention of venous thromboembolism after major orthopaedic surgery and in hospitalised acutely ill medical patients[J].Thromb Haemost,2012,107(6):1027-1034.
  • 8Wood J,Butler CC,Hood K,et al.Antibiotic prescribing for adults with acute cough/lower respiratory tract infection:congruence with guidelines[J].Eur Respir J,2011,38(1):112-118.
  • 9Pfister R,Kochanek M,Leygeber T,et al.Procalcitonin for diagnosis of bacterial pneumonia in critically ill patients during 2009H1N1influenza pandemic:aprospective cohort study,systematic review and individual patient data meta-analysis[J].Crit Care,2014,18(2):R44.
  • 10Kwon JM,Shim JW,Kim DS,et al.Prevalence of respiratory viral infection in children hospitalized for acute lower respiratory tract diseases,and association of rhinovirus and influenza virus with asthma exacerbations[J].Korean J Pediatr,2014,57(1):29-34.

共引文献87

同被引文献21

引证文献2

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部