B超引导下甲氨蝶呤局部注射治疗输卵管妊娠的临床效果分析

Clinical analysis of local injection of methotrexate in treatment of tubal pregnancy under B ultrasound guidance

目的探究在输卵管妊娠治疗时,使用B超引导下甲氨蝶呤局部注射的效果。方法选取2015年1月～2016年7月湖州市妇幼保健院收治的80例输卵管妊娠患者,随机分为对照组和观察组,每组40例。对照组患者采用常规肌肉给予甲氨蝶呤,观察组在B超引导下甲氨蝶呤局部注射。观察2组患者干预效果并进行比较。结果观察组血HCG恢复时间为（22.35±1.05）天,对照组患者均值为（34.26±1.32）天,观察组患者血HCG恢复时间明显快于对照组（P〈0.05）;观察组治疗成功率和输卵管通畅率均高于对照组,2组比较差异具有统计学意义（P〈0.05）。结论 B超引导下甲氨蝶呤局部注射治疗输卵管妊娠能够快速提高患者的局部药物浓度,改善患者临床情况,起到较好的治疗效果。

Objective To explore the treatment of tubal pregnancy,the use of ultrasound guided methotrexate local injection effect.Methods A total of 80 patients with tubal pregnancy who were enrolled in our hospital from January 2015 to July 2016 were randomly divided into control group and observation group（n=40）.The patients in the control group were given methotrexate by conventional muscle,and the observation group was injected with methotrexate under the guidance of B ultrasound.Observe and compare the treatment of two groups of patients.Results The recovery time of HCG in the observation group was（22.35±1.05） days,the mean value of the control group was（34.26±1.32） days,the recovery time of HCG in the observation group was significantly faster than that in the control group（P〈0.05）.Tubal patency rate was higher than the control group,the difference between the two groups was statistically significant（P〈0.05）.Conclusion B-ultrasound guided methotrexate local injection treatment of tubal pregnancy can rapidly improve the patient＇s local drug concentration,it can rapidly improve The local drug concentration of the patient can improve the clinical situation of the patient,and has better therapeutic effect,so it is worthy of clinical reference.