异丙托溴铵联合硫酸特布他林雾化吸入治疗哮喘急性发作的临床分析

Clinical analysis of ipratropium bromide combined with terbutaline sulfate inhalation in the treatment of acute attack of asthma

目的分析异丙托溴铵联合硫酸特布他林雾化吸入治疗哮喘急性发作的临床效果。方法选取杭州拱墅区祥符街道社区卫生服务中心2015年3月～2016年10月收治的100例哮喘急性发作患者为研究对象,随机分为对照组和实验组,每组50例。对照组患者进行硫酸特布他林雾化吸入治疗,实验组患者采用异丙托溴铵联合硫酸特布他林雾化吸入治疗。2组患者均持续治疗7 d,比较分析2组患者治疗效果。结果经过相应治疗后,实验组患者的治疗有效率（94.0%）显著高于对照组患者（72.0%）,差异有统计学意义（P〈0.05）。对照组患者呼吸困难、啰音以及咳嗽等临床症状改善时间显著长于实验组,差异有统计学意义（P〈0.05）。结论异丙托溴铵联合硫酸特布他林雾化吸入治疗哮喘急性发作临床疗效较好,改善临床症状时间较短。

Objective To analyze the clinical efficacy of ipratropium bromide combined with terbutaline sulfate inhalation in the treatment of acute attack of asthma.Methods 100 patients with acute attack of asthma treated from March 2015 to October 2016 were selected and randomly divided into the control group and the experimental group,with 50 patients in each group.The control group received terbutaline sulfate inhalation,and the experimental group received ipratropium bromide combined with terbutaline sulfate inhalation treatment.The patients in the experimental group and the control group were treated for 7 days continuously.The therapeutic effects of the two groups were compared and analyzed.Results After the corresponding treatment,the effective rate of treatment in the experimental group（94.0%） was significantly higher than that in the control group（72.0%）,the difference was statistically significant（P〈0.05）.The improvement time of dyspnea,rale and cough in control group was significantly longer than that in the experimental group,the difference was statistically significant（P〈0.05）.Conclusion Ipratropium bromide combined with terbutaline sulfate inhalation in the treatment of acute attack of asthma has better clinical efficacy and shorter clinical symptoms.