全天麻胶囊联合氟哌噻吨美利曲辛片治疗慢性偏头痛的临床效果观察

Clinical effect of Quantianma capsules combined with flupentixol and melitracen tablets on chronic migraine

目的观察全天麻胶囊联合氟哌噻吨美利曲辛片治疗慢性偏头痛的临床效果。方法 130例慢性偏头痛患者分为对照组和观察组,每组各65例,均进行氟哌噻吨美利曲辛片治疗,其中观察组另给予全天麻胶囊。结果总有效率方面,观察组（90.77%）高于对照组（73.85%）（P〈0.05）。经治疗,2组偏头痛发作次数、单次持续时间、VAS评分、HAMA和HAMD得分以及脑动脉平均血流速度均低于治疗前,且观察组均低于对照组（均P〈0.05）。不良反应方面,2组差异无统计学意义。结论全天麻胶囊可配合氟哌噻吨美利曲辛片可提高慢性偏头痛治疗疗效,改善病情,且无不良反应。

Objective To analyse the clinical effect of Quantianma capsules combined with flupentixol and melitracen tablets on chronic migraine.Methods 130 patients with chronic migraine were treated with flupentixol and melitracen tablets,were divided into control group and observation group,65 patients in each group.The observation group were given to Quantianma capsules.Results The effective rate of observation group with 90.77% was higher than control group with 73.85%（P〈0.05）.After treatment,the number of migraine attacks,duration time,VAS score,HAMA and HAMD score and mean flow velocity of cerebral artery of two groups were lower than pre-treatment and observation group were lower than that of control group（P〈0.05）.Adverse reactions were similar in the two groups.Conclusion Quantianma capsules can improve the efficacy of treatment of chronic migraine combined with flupentixol and melitracen tablets and improve condition with few adverse effects.