参附汤加味联合西医规范治疗老年多脏器功能衰竭的临床观察

Clinical observation on supplemented shenfu decoction combined with western medicine in the treatment of multiple organ failure in the elderly

目的探究参附汤加味心联合西医规范治疗老年多脏器功能衰竭（multiple organ failure,MOF）的临床效果。方法选取65例老年MOF患者为研究对象,随机分为观察组（n=35）和对照组（n=30）。2组均给予常规规范西医治疗,观察组在此基础上联合参附汤加味治疗。结果治疗后,2组血压、尿量均明显升高（P〈0.05）,且观察组显著高于对照组（P〈0.05）;2组患者呼吸、心率均明显降低（P〈0.05）,且观察组显著低于对照组（P〈0.05）;2组Scr、BUN、UA水平均明显下降（P〈0.05）,且观察组显著低于对照组（P〈0.05）;治疗后2组IL-6、CRP、TNF-α水平明显降低（P〈0.05）,且观察组显著低于对照组（P〈0.05）。结论探究参附汤加味联合西医规范治疗老年多脏器功能衰竭（MOF）应用临床效果可观显著。

Objective To explore the effect of Shenfu Decoction combined with western medicine treatment of elderly patients with multiple organ dysfunction syndrome（MOF） clinical effect.Methods 65 cases of elderly patients with MOF as the research object,were randomly divided into observation group（n=35） and control group（n=30）.The two groups were given conventional standard western medicine treatment,the observation group on the based on the combination of Shenfu Decoction treatment.Results After treatment,two groups of blood pressure and urine volume were significantly increased（P〈0.05）,and the observation group was significantly higher than the control group（P〈0.05）;the two groups of patients with respiratory and heart rate were significantly decreased（P〈0.05）,and the observation group was significantly lower than the control group（P〈0.05）;two groups of Scr,BUN,UA were significantly decreased（P〈0.05）,and the observation group was significantly lower than the control group（P〈0.05）;the two groups after treatment IL-6,CRP,TNF-α levels decreased significantly（P〈0.05）,and the observation group was significantly lower than the control group（P〈0.05）.Conclusion Shenfu Decoction combined with western standard clinical effect in treatment of elderly MOF is considerable.