万古霉素与美罗培南联合腰大池外引流治疗颅脑损伤术后颅内感染的疗效及心理干预的效果分析

Vancomycin and meropenem combined with lumbar cistern drainage and curative effect of psychological intervention on the basis of the analysis of intracranial infection in treatment of brain injury after operation

目的探讨颅脑损伤术后并发颅内感染的患者在应用万古霉素、美罗培南与腰大池外引流联合治疗的疗效及采用心理干预的临床价值。方法选择颅脑损伤术后并发颅内感染的患者55例,均为嘉兴市第三医院神经外科2012年7月～2017年7月收治,在应用万古霉素、美罗培南与腰大池外引流联合治疗的基础上,重视心理护理的实施。结果本组临床总有效率为94.6%;相较治疗前,治疗后脑脊液白细胞计数、蛋白质水平明显降低,葡萄糖水平明显升高,差异均具有统计学意义（P〈0.05）。相较干预前,干预后心理状况评分明显改善,差异具有统计学意义（P〈0.05）。结论颅脑损伤术后合并颅内感染的患者,在应用万古霉素、美罗培南与腰大池外引流联合治疗的基础上,加用心理护理,可提高临床总有效率,改善心理状况。

Objective To explore the basis of intracranial infection after craniocerebral operation with drainage combined with treatment in the application of vancomycin,meropenem and lumbar cistern on the use of psychological intervention clinical value.Methods 55 cases with intracranial infection craniocerebral injury patients were admitted to the Department of neurosurgery in Third Hospital of Jiaxing City in July 2012 to July 2017,the basic treatment in the application of drainage combined with vancomycin,meropenem and lumbar abroad,pay attention to the implementation of psychological nursing.Results The total effective rate of the group was 94.6%.Compared with before treatment,the number of WBC and protein in CSF decreased significantly,and the level of glucose increased significantly,with statistical difference（P〈0.05）.Compared with the intervention,the psychological status score improved obviously after intervention,with statistical difference（P〈0.05）.Conclusion The patients with craniocerebral injury complicated with intracranial infection after operation,basic drainage combined with treatment in application of meropenem and vancomycin,lumbar cistern on the use of psychological nursing,can improve the total clinical efficiency,improve psychological status.