期刊文献+

经尿道膀胱肿瘤电切术后患者应用吡柔比星早期膀胱灌注的临床观察及心理干预

Clinical observation of early intravesical instillation of pirarubicin after transurethral resection of bladder tumor and psychological intervention to patients
下载PDF
导出
摘要 目的讨论经尿道膀胱肿瘤电切术后患者应用吡柔比星早期膀胱灌注的临床效果以及心理干预措施。方法选取2015年8月~2016年12月在温州市中心医院进行经尿道膀胱肿瘤电切术,且术后给予吡柔比星早期膀胱灌注治疗的患者86例作为研究对象,随机分成实验组43例和对照组43例,对照组在经尿道膀胱肿瘤电切术后采取常规药物化疗方案,实验组术后采取早期实施吡柔比星治疗方案,对2组患者术后膀胱肿瘤复发率进行对比和分析,同时给予2组患者心理护理,探讨心理护理实施措施的效果。结果实验组患者的复发率为9.3%,明显高于对照组的18.6%,组间差异具有统计学意义(P〈0.05);2组患者给予心理护理后发现提升了患者的治疗心理,增加了治疗的依从性。结论在经尿道膀胱肿瘤电切术后给予吡柔比星早期膀胱灌注能够有效的降低术后膀胱肿瘤的复发率,在治疗过程中给予心理护理,能够提升患者在治疗中的耐受性,提升了治疗的依从性。 Objective To discuss the clinical effect of early bladder instillation of pirarubicin after transurethral resection of bladder tumor and the psychological intervention measures.Methods 86 patients from August 2015 to December 2016 for transurethral resection of bladder tumor treated with pirarubicin(PHT) early intravesical therapy were divided randomly into experimental group 43 cases and control group 43 cases,control group in transurethral resection of bladder tumor after transurethral resection take the routine drug regimen,early implementation of pirarubicin therapy after surgery in the experimental group,to compare and analyze the recurrence of bladder cancer after operation in the two groups,and two groups of patients were given psychological nursing,to explore the implementation and effect of psychological nursing measures.Results The patients in the experimental group the recurrence rate was 9.3%,significantly higher than the control group 18.6%,the differences between groups was statistically significant(P〈0.05);two groups of patients were given psychological nursing was found to improve patient psychological treatment,increase treatment compliance.Conclusion THP in transurethral resection of bladder tumor after star early bladder irrigation can effectively reduce the recurrence rate of bladder cancer after operation,psychological nursing in the treatment process,can enhance the tolerance in the treatment of patients,improve the treatment compliance,is worthy of clinical popularization and application.
作者 林晨莉
出处 《中国生化药物杂志》 CAS 2017年第10期308-309,共2页 Chinese Journal of Biochemical Pharmaceutics
关键词 吡柔比星 膀胱灌注 心理干预 pirarubicin bladder instillation psychological intervention
  • 相关文献

参考文献8

二级参考文献62

  • 1安瑞,赵玉宝,高平.经尿道膀胱肿瘤电切术后膀胱灌注吡柔比星治疗浅表性肿瘤的疗效观察[J].中国药物与临床,2012,12(S1):38-40. 被引量:17
  • 2张端卫,冀荣俊,蒋敏,王胜利.经尿道汽化电切术治疗浅表性膀胱癌31例[J].蚌埠医学院学报,2007,32(2):173-175. 被引量:10
  • 3钱本江,李惠长.吡柔比星与丝裂霉素膀胱灌注预防人膀胱癌复发比较的Meta分析[J].国际外科学杂志,2007,34(5):294-296. 被引量:26
  • 4Kaufman DS,Shipley WU,Feldman AS.Bladder cancer[J].Lancet,2009,374(9685):239-249.
  • 5Jemal A,Murray T,Ward E,et al.Cancer statistics,2005[J].CA Cancer J Clin,2005,55(1):10-30.
  • 6Knowles MA.Bladder cancer subtypes defined by genomic alterations[J].Stand J Urol Nephrol Suppl,2008(218):116-130.
  • 7Mak RH,zl Etman AL,Heney NM,et al.Bladder preservation optimizing radiotherapy and integrated treatment strategies[J].BJU Int,2008,102(9):1345-1353.
  • 8Maruyama T,Higuchi Y,Suzuki T,et al.Double short-time exposure to pirarubicin produces higher cytotoxicity against T24 bladder cancer cells[J].J Infect Chemother,2011,17(1):11-16.
  • 9Kobayashi S,Oka K,Machida T,et al.5 years intravesical instillation with mitomycin-C and pirarubicin as a prophylactic treatment for superficial bladder cancer[J].Nippon Hinyokika Gakkai Zasshi,2006,97(4):636-641.
  • 10吴阶平 裘法祖.黄家驷外科学[M].北京:人民卫生出版社,1999.829-830.

共引文献35

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部