非离子型对比剂碘佛醇在CT静脉增强中的临床应用研究

Clinical study of nonionic contrast agents in the enhancement of intravenous CT

目的探讨CT静脉增强扫描中非离子型对比剂碘佛醇应用成效。方法选取浙江省温岭市第一人民医院2016年1月～12月收治的84例行CT静脉增强扫描检查患者,碘佛醇用量为80～100 mL,注射速度为3～6 mL/s,均在增强扫描前2 h及增强扫描后即刻、扫描后1 h、48 h对生命体征记录,观察注射部位,检查心电图,在增强扫描前2 h和增强扫描后48 h,行血液生化指标检查及肾功能检查,且在增强扫描时及扫描后即刻、扫描后15 min、1 h、48 h等不同时间段对不良反应分别观察并记录。结果碘佛醇注射后,全身耐受优良率为100%,有潮红及热感7例,占8.3%;轻度不良反应1例,占1.2%,无中、重度不良反应发生。结论在CT静脉增强扫描中应用非离子型对比剂碘佛醇,不良反应率居较低水平,具较高安全性。

Objective To evaluate the efficacy of nonionic contrast agent,CT,in intravenous enhanced scan.Methods 84 cases of patients with CT venous enhancement scanning were admitted in our hospital from January 2016 to December 2016,ioversol dosage is 80~100 mL,the injection speed is 3~6 mL/s,both in the scan and enhanced scan before 2 h,immediately after scanning after 1 h,48 h to record vital signs,observation of the injection site,ECG,enhanced scan in the 2 h before and after 48 h enhancement scanning,blood biochemical examination and renal function tests,and immediately,in enhanced scan and scan after scan after 15 min,1 h and 48 h in different time periods of adverse reactions were observed and recorded.Results The excellent rate of systemic tolerance was 100%,7 cases had flushing and thermal sensation,accounting for 8.3%.Slight adverse reactions occurred in 1 cases,accounting for 1.2%.No moderate or severe adverse reactions occurred.Conclusion The use of non-ionic contrast agent CT in intravenous enhanced scan,low adverse reaction rate,high safety,and has a very important application value.