不同浓度碘普罗胺强化剂对肝组织CT成像效果与不良反应对比研究

Comparative study on the effects of different concentrations of Iopromide Injection on liver tissue imaging and adverse reactions

目的探讨不同浓度碘普罗胺注射液对肝组织成像效果与不良反应对比研究。方法选取150例肝脏无实质性病变的患者,随机分为A组、B组和C组,每组50例,在进行了上腹部的平扫之后,注射碘普罗胺注射液对腹主动脉、门静脉主干、5处肝组织进行增强扫描,评价强化值及观察不良反应,比较不同浓度碘普罗胺注射液对肝组织成像效果与不良反应。结果 A组注射370 mg/mL碘普罗胺注射液后腹主动脉强化值为249.21,门静脉强化值为132;B组注射350 mg/mL碘普罗胺注射液后门静脉强化值为229.32,门静脉强化值为121.32;C组注射300 mg/mL碘普罗胺注射液后肝组织强化值为239.21,门静脉强化值为98.32,A组与B组,C组之间差异具有统计学意义（P〈0.05）。3组患者不良反应发生情况比较差异无统计学意义。结论浓度升高成像效果更好,患者服用高浓度对比剂与低浓度对比剂之后产生的不良反应无显著差异。

Objective To investigate the effects of different concentrations of iopromide injection on liver tissue imaging and adverse reactions.Methods Selected 150 patients of liver without substantial disease patients,were randomly divided into A group（n=50） and B group（n=50） and C group（n=50）,after the abdominal plain,Iopromide Injection injection enhanced scan of the abdominal aorta,portal vein,5 hepatic tissue,strengthen the evaluation value and the adverse reactions were observed,compared with different concentrations of Iopromide Injection imaging effect and adverse reaction of liver tissue.Results A group was injected with 370 mg/mL Iopromide Injection after abdominal aorta was 249.21,the enhancement of portal vein was 132,B group were injected with 350 mg/mL value of 229.32 Iopromide Injection portal vein enhancement,portal vein enhancement value was 121.32,C group were injected with 300 mg/mL Iopromide Injection hepatic enhancement value was 239.21,the enhancement of portal vein was 98.32,the A group and B group,there was significant difference with C group（P〈0.05）.There was no significant difference in adverse reactions between the three groups when injected with different concentrations of iopromide injection.Conclusion The results show that the imaging effect is better with the increase of concentration,and there is no significant difference between the patients with high concentration contrast agent and low concentration contrast agent.