西安某医院2007—2016年带状疱疹流行及回顾性研究

The Epidemic of Herpes Zoster in Specific Hospital in Xi'an City:A Retrospective Study from 2007 to 2016

目的分析西安某医院带状疱疹病例的临床流行病学特征,为进一步开展带状疱疹防治工作提供科学依据。方法纳入2007—2016年9年期间西安某医院收治的带状疱疹住院患者2 743例,回顾性分析其一般人口学特征、现病史、既往史、入院时间、住院天数、主要诊断等相关信息,探索影响住院时间的相关因素。结果带状疱疹患者人数呈现逐年增加的趋势;特殊类型的带状疱疹和运动神经受累的患者中,女性比例较大;药物治疗方案的改变是住院时间减短的主要原因(OR=4.618,95%CI:2.494~8.542),年龄组不同(老年组OR=2.050,95%CI:1.411~2.980)、入院诊断不同(出血坏死性带状疱疹OR=2.001,95%CI:1.324~3.050)、运动神经受累(OR=1.381,95%CI:1.095~1.742)也是影响住院时间的因素。结论带状疱疹患病数量逐年增加,应进一步结合不同地区、不同中心的门诊/住院患者数据,探索我国带状疱疹临床流行病学特征,制订有效的预防措施。

Objectives To analysis the clinical epidemiology characteristics of the herpes zoster（HZ）in specific hospital in Xi＇an,and provide scientific basis for HZ prevention and therapy.Methods 2 743 herpes zoster inpatients from 2007 to 2016 in the hospital were included in the research.Retrospective study design was used to analysis the epidemiology characteristics of demography,history of present illness,date of admission,days in hospital and primary diagnosis,to explore the factors of hospital stays.Results There was an increasing trends of HZ inpatient number in the hospital these years.The number of female was more than male in special types of HZ and motor nerve involvement cases.The therapeutic schedule was the main factor for hospital stay（OR=4.618,95%CI：2.494-8.542）,also the older age（OR=2.050,95%CI：1.411-2.980）,admitting diagnosis（OR=2.001,95%CI：1.324-3.050）,whether the motor nerve involved（OR=1.381,95%CI：1.095-1.742）were factors for hospital stay.Conclusions The number of herpes zoster patients increased gradually these years,it was necessary to integrate data from different region,different hospital to know the rule of HZ epidemic,and to make policies for HZ prevention.