他汀类药物对老年急性脑梗死进展与神经功能的影响

Effects of statins on the progression and neurological function of elderly patients with acute cerebral infarction

目的探讨他汀类药物对老年急性脑梗死进展与神经功能的影响。方法随机选取2014年—2016年收治的患有急性脑梗死的患者90例作为本次的研究对象,并按照治疗方式的不同将患者分为常规组和观察组两组,两组患者均采用常规的药物对患者进行治疗,观察组的患者在此基础上联合使用瑞舒伐他汀药物对患者进行治疗,治疗结束后,对两组患者的临床治疗效果进行对比。结果观察组患者的NHISS的评分要明显小于常规组的患者,且患者病情高峰的时间也明显少于常规组,观察组临床治疗的总有效率为93.33%,要明显高于常规组的治疗总有效率71.11%,观察组患者的BI评分要显著高于常规组,两组数据结果的对比存在较大差异(P<0.05),在统计学上具有意义。结论在常规治疗的基础上使用瑞舒伐他汀药物对患者进行治疗,能够显著提高治疗效果,减小对患者神经功能的损伤,缩短治疗时间,提高患者生活质量,效果显著,值得在临床治疗中广泛推广及应用。

Objective： To investigate the effect of statins on the progression and neurological function of acute cerebral infarction in the elderly. Methods： Ninety patients with acute cerebral infarction were randomly selected from 2014 to 2016.December. The patients were divided into two groups： the conventional group and the observation group according to the different treatment methods. Patients were treated with conventional drugs. The patients in the observation group were treated with rosuvastatin and the patients were treated with rosuvastatin. After the treatment,the clinical efficacy of the two groups was compared. Results： The scores of NHISS in the observation group were significantly lower than those in the conventional group,and the peak time of the patients was significantly lower than that of the conventional group. The total effective rate of clinical treatment was 93. 33% in the observation group,which was significantly higher than that in the conventional group（ P〈0. 05）,and there was significant difference between the two groups（ P〈0. 05）,and the data of the two groups were significantly higher than those of the conventional group（ P〈0. 05）. Conclusion： Treatment of patients with rosuvastatin on the basis of conventional therapy can significantly improve the clinical treatment effect,reduce the damage of nerve function,shorten the treatment time and improve the quality of life of patients,the effect is remarkable,Worthy of clinical treatment in a wide range of promotion and application.