早产儿脑发育过程中振幅整合脑电图的变化及临床意义

Changes of Amplitude Integrated Electroencephalogram in Preterm Infants during Brain Development and Its Clinical Significance

目的:探究振幅整合脑电图在早产儿脑发育过程中的变化规律以及其相应的临床意义。方法:选取120例不同孕龄的早产儿,然后用脑功能监护仪对不同孕龄早产儿的a EEG波谱带的变化,分析在早产儿脑发育过程中a EEG各项指标的变化规律。结果:出现a EEG背景连续性和睡眠-觉醒周期的概率随着孕龄的增加而增加,孕龄大于34周的早产儿显著高于其他孕龄的早产儿(P<0.05);而且脑电波下边界振幅随着孕龄的增高而增高,带宽则下降。结论:不同孕龄的早产儿脑发育过程中的振幅整合脑电图有着一定的变化规律,为临床诊断早产儿脑发育程度提供了较可靠的科学依据。

Objective： To investigate the change rules of amplitude integrated electroencephalogram（ EEG） in preterm infants during brain development and its clinical significance. Methods： 120 cases of preterm infants in different gestational age were selected and then changes of a EEG spectrum of different gestational age in preterm infants were monitored by the cerebral function monitor instrument with the analysis of the variation in a EEG indicators in the process of brain development of premature infants. Results： The probability of a EEG background continuity and sleep wake cycle increased with the increase of gestational age. The probabilities of preterm infants belonging to gestational age more than34 weeks of gestational age were significantly higher than those in other preterm infants（ P 0. 05）. with the increase of amplitude of brain waves under the boundary,the gestational age increased meanwhile with the bandwidth reduction.Conclusions： The amplitude and integration of electroencephalogram in the brain development of preterm infants with different gestational age have some certain change rules,which provides a reliable scientific basis for clinical diagnosis of brain development in premature infants.