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门冬胰岛素和生物合成人胰岛素治疗妊娠期糖尿病疗效观察 被引量:9

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摘要 目的观察门冬胰岛素和生物合成人胰岛素在治疗妊娠期糖尿病中的疗效和安全性。方法在我院2015年3月至2016年8月收治的妊娠期糖尿病患者中选出135例随机分成A组和B组,A组患者给予门冬胰岛素治疗,B组患者给予生物合成人胰岛素治疗,对比两组患者的血糖水平、母婴结局等指标值。结果 A组患者治疗前和治疗3d时的空腹血糖、餐后2h血糖与对照组对比差异不明显(P>0.05);治疗5d时,A组患者的空腹血糖、餐后2h血糖均低于B组,且A组患者的血糖达标时间更短,胰岛素日平均用量低于B组(P<0.05);A组产妇并发症发生率与B组差异无统计学意义(P>0.05);A组新生儿并发症发生率低于B组(P<0.05)。结论在妊娠期糖尿病治疗中门冬胰岛素的降血糖效果更好,且有助于改善母婴结局,减少胰岛素用量。
作者 陈捷 王桂芳
出处 《青岛医药卫生》 2017年第5期363-364,共2页 Qingdao Medical Journal
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  • 1周巍巍,黄亚薇,李悦平.门冬酸胰岛素30注射液及精蛋白生物合成人胰岛素(预混30R)治疗2型糖尿病疗效观察[J].当代医学,2008,14(14). 被引量:3
  • 2Gonz'alez-Quintero VH, Istwan NB, Rhea DJ, et al. The impact of glycemic control on neonatal outcome in singleton pregnancies complicated by gestational diabetes. Diabetes Care ,2{D7 ,30 :467-470.
  • 3DCCT Research Group. Pregnancy outcomes in the Diabetes Control and complications Trial. Am J Obstet Gynecol 1996,174: 1343-1353.
  • 4Lindholm A, McEwen J, Riis AP. Improved postprandial glycemic control with insulin aspart:a randomized, double-blind cross over trial in type 1 diabetes. Diabetes Care ,1999 ,22 :801-805.
  • 5Heller SR, Colagiuri S, Vaaler S, et al. Hypoglycaemia with insulin aspart : a double-blind, randomised, crossover trial in subjects with type 1 diabetes. Diabet Med,2004,21:769-775.
  • 6Pettitt DJ, Ospina P, Kolaczynski JW, et al . Comparison of an insulin analog, insulin aspart, and regular human insulin with no insulin in gestational diabetes mellitus. Diabetes Care, 2003,26: 183-186.
  • 7Manthiesen ER, Kinsley B, Amiel SA, et al. Manternal glycemic control and hypoglycemia in type Ⅰ diabetic pregnancy: a randomized trial of insulin aspart versus human insulin in 322 pregnant women. Dabetes Care, 2007,30:771-776.
  • 8Pettitt D J, Ospina P, Howard C, et al. Efficacy, safety and lack of immunogenicity of insulin aspart compared with regular human insulin for women with gestational diabetes mellitus. Diabet Med, 2007,24:1129-1135.
  • 9Hod M, Damm P, Kaaja R, et al. Fetal and perinatal outcomes in type Ⅰ diabetes pregnancy:a randomized study comparing insulin aspart with human insulin in 322 subjects. Am J Obstet Gynecol, 2008,198 :e1-186-e7.
  • 10Gui J, Liu Q, Feng L. Metformin vs insulin in the management of gesta- tional diabetes: a meta- analysis [J]. PLoS One, 2013, 8 (5) : e64585.

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