养血清脑颗粒联合奥拉西坦对脑梗死认知功能障碍的疗效

Effect of Yangxue Qingnao granule combined olasetan in the treatment of cognitive dysfunction in patients with cerebral infarction

目的探讨联合用药治疗脑梗死认知功能障碍患者的临床效果。方法选择2014-03-2016-03漯河医学高等专科学校第二附属医院收治的脑梗死认知功能障碍患者80例。对照组40例给予奥拉西坦单药治疗,观察组40例在对照组基础上给予养血清脑颗粒治疗。比较2组认知功能改善情况。结果治疗前2组MMSE各项评分比较差异无统计学意义(P>0.05);治疗后2组MMSE各项评分均有改善,其中观察组各项评分显著高于对照组(P<0.05)。治疗后,对照组和观察组治疗有效率分别为75.0%和95.0%,差异有统计学意义(P<0.05)。结论脑梗死认知功能障碍患者采用奥拉西坦联合养血清脑颗粒治疗效果显著,认知功能障碍可得到有效改善,促进患者恢复,值得在临床中推广应用。

Objective To investigate the clinical effect of combined therapy in the treatment of cognitive dysfunction in patients with cerebral infarction.Methods 803 patients with cognitive impairment were enrolled in this study.All patients were treated with drugs.In the control group,40 patients were treated with olasetan monotherapy,and 40 cases in the observation group were treated with additional Yangxue Qingnao granule.The cognitive function of the two groups were compared.Results There were no significant differences in MMSE scores between the two groups before treatment(P>0.05).The scores of MMSE were improved in the two groups after treatment,and the scores of MMSE were significantly higher in the observation group than that in the control group(P <0.05).After treatment,the effective rates were 75.0% and 95.0% in the control and observation groups,respectively.There was significant difference between the two groups(P<0.05).Conclusion The combined treatment in patients with cognitive impairment is significant.It can improve the cognitive function,promote the recovery in the patients and is worthy to be popularized in clinical practice.