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血清CA125与CEA联合检测在宫颈癌诊断中的临床价值研究 被引量:2

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摘要 目的探讨血清糖链抗原125(CA125)和癌胚抗原(CEA)联合检测在宫颈癌诊断中的临床价值。方法选取2015年6月至2017年1月平顶山市中医院收治的60例宫颈癌患者作为观察组,选取同期在平顶山市中医院体检的60例健康女性作为对照组。采用电化学发光法检测两组受检者血清CA125与CEA水平。结果观察组患者血清CA125和CEA的平均水平高于对照组,血清CA125、CEA单独及联合检测阳性率均高于对照组,差异均有统计学意义(P<0.05);观察组患者血清CA125与CEA联合检测阳性率高于单独检测阳性率,差异有统计学意义(P<0.05);观察组患者中Ⅲ~Ⅳ期患者血清CA125、CEA单独检测及联合检测阳性率均高于Ⅰ、Ⅱ期患者,Ⅱ期患者血清CA125、CEA单独检测及联合检测阳性率均高于Ⅰ期患者,且不同临床分期联合检测阳性率均高于两项指标单独检测阳性率,差异均有统计学意义(P<0.05)。结论血清CA125与CEA联合检测对宫颈癌的诊断有很高的临床价值,且可根据肿瘤标志物检测水平协助判断宫颈癌患者的临床分期,值得临床推广应用。
作者 樊振兴
出处 《河南医学研究》 CAS 2017年第20期3719-3720,共2页 Henan Medical Research
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