大学生物化学课程“酶动力学”教学之我见

Insights into teaching enzyme kinetics in college biochemistry course

酶动力学是大学生化课程教学的重要内容,旨在培养学生分析酶和配体相互作用的基本能力。随着生物医学体外研究技术的兴起,分析酶-配体相互作用将会成为研究者必备的基本技能,但是当前酶动力学的教学内容并不能达到这一目标。本文从科学研究实际出发,重点讨论现行酶动力学教学的不足,认为在该部分的教学中应加入动力学模型构建和非米氏动力学的内容。

Enzyme kinetics acts as an important chapter in college biochemistry course. The chapter aims at endowing students with fundmental skills in analyzing interactions of enzymes with its ligants. This paper disccuses several current pitfalls in teaching enzyme kinetics. From the view of the fast development of in vitro methods, we conclude that atypical kinetics and how to construct kinetic model should be included as basic requirements in teaching.