代谢综合征与缺血性脑卒中患者转归不良的相关性研究

Study on correlation between metabolic syndrome and the poor outcome of ischemic stroke patients

目的探讨代谢综合征(MS)与缺血性脑卒中患者转归不良的相关性。方法收集2015年1月~2016年4月在新疆奎屯第七师医院神经内科收治的427例急性缺血性脑卒中患者的临床资料。根据发病后90 d mRS评分将患者分为转归不良组和转归良好组。采用多因素Logistic回归进行MS与缺血性脑卒中转归不良的相关性分析。结果转归不良组NIHSS评分≥15分、后循环梗死、肺部感染和MS的比例均高于转归良好组(均P<0.05);NIHSS评分≥15分(OR=8.615,95%CI:5.305~13.991,P=0.000)、MS(OR=2.226,95%CI:1.373~3.609,P=0.001)是转归不良的独立危险因素。结论 NIHSS评分≥15分和MS都是缺血性脑卒中患者转归不良的独立危险因素。

Objective To investigate the correlation between metabolic syndrome（ MS） and the poor outcome of ischemic stroke patients. Methods The clinical data of 427 ischemic stroke patients treated in the 7 th division hospital of Xinjiang production and construction corps from January 2015 to April 2016 were collected. According to the mRS scores at 90 d after onset,all the patients were divided into poor outcome group and good outcome group.Multivariate Logistic regression analysis was used to analyze the relationship between MS and the poor outcome of ischemic stroke patients. Results The ratios of NIHSS scores ≥ 15,posterior circulation infarction,pulmonary infection and MS in poor outcome group were significantly higher than those in good outcome group（ all P〈0. 05）.NIHSS scores≥15（ OR = 8. 615,95% CI： 5. 305-13. 991,P = 0. 000）,MS（ OR = 2. 226,95% CI： 1. 373-3. 609,P = 0. 001） were the independent risk factors of poor outcome. Conclusions NIHSS scores ≥15 and MS both are the independent risk factors of poor outcome.