幽门螺杆菌相关性慢性胃炎中医证型分布研究

TCM syndrome types of Helicobacter pylori-associated gastritis

目的:观察幽门螺杆菌相关性慢性胃炎(Helicobacter Pylori Associated Gastritis,HPAG)的中医证型分布情况。方法:将400例慢性胃炎患者按中医辨证分为肝郁气滞、肝胃郁热、脾胃湿热、胃络瘀阻、脾胃虚寒、胃阴不足6个证型,同时检测Hp感染情况。结果:慢性非萎缩性胃炎(Chronic Non-atrophy Gastritis,CSG)中医证型分布由高到低依次为脾胃湿热证>肝郁气滞证>肝胃郁热证>胃络瘀阻证>脾胃虚寒证>胃阴不足证,慢性萎缩性胃炎(Chronic Atrophic Gastritis,CAG)中医证型分布由高到低依次为脾胃湿热证>胃络瘀阻证>肝郁气滞证>肝胃郁热证>胃阴不足证>脾胃虚寒证。各证型Hp感染率分布由高到低依次为脾胃湿热证>肝郁气滞证>肝胃郁热证>胃络瘀阻证>脾胃虚寒证>胃阴不足证,脾胃湿热证与其他证型相比,差异有统计学意义(P<0.05)。结论:HPAG临床以脾胃湿热证最为多见。

Objective：To investigate the traditional Chinese medicine （TCM）syndrome types of Helicobacter pylori （HP） -associated gastritis（HPAG）. Methods：A total of 400 patients with HPAG were divided into six TCM syndrome types ： liver qi stagnation, liver - stomach heat accumulation, spleen - stomach damp heat, gastric collateral stasis, deficient cold of spleen and stomach, and stomach - yin deficiency. These patients were examined to detect Hp infection. Results ： In patients with chronic non - atrophic gastritis, the most common syndrome type was spleen - stomach damp heat, followed by liver qi stagnation, liver - stomach heat accumulation, gastric collateral stasis, deficient cold of spleen and stomach, and stomach- yin deficiency. In patients with chronic atrophic gastritis, the most common syndrome type was also spleen - stomach damp heat, followed by gastric collateral stasis, liver qi stagnation, liver - stomach heat accumulation, stomach - yin deficiency, and deficient cold of spleen and stomach. The syndrome of spleen - stomach damp heat showed the highest Hp infection rate, followed by liver qi stagnation,liver - stomach heat accumulation, gastric collateral stasis, deficient cold of spleen and stomach, and stonmch - yin deficiency, and there was a significant difference in lip infection rate between patients with spleen - stomach damp heat and those with other syndromes （P 〈 0. 05 ）. Conclusion ： Spleen - stomach damp heat is the most common TCM syndrome in patients with HPAG.