小功率钬激光前列腺剜除术在良性前列腺增生治疗中的临床价值

Clinical value of low power holmium laser enucleation in the treatment of benign prostatic hyperplasia

目的 评价小功率钬激光前列腺剜除术用于良性前列腺增生治疗中的临床价值.方法 选择2012年1月至2015年6月本院收治的良性前列腺增生患者312例,将患者随机分为两组,观察组为行小功率钬激光前列腺剜除术组,对照组为行经尿道前列腺电切术组,每组156例.比较两组手术时间、切除增生重量、术后血清Na＋、血Hb、并发症、导尿管留置时间、住院时间以及术后最大尿流率（Qmax）、国际前列腺症状评分（IPSS）、生活质量评分（QOL）、血清前列腺特异性抗原（PSA）.结果 两组患者围手术期指标结果显示,观察组切除标本重量、血清Na＋、Hb、术后冲洗时间、尿管留置时间、术后住院时间及并发症等与对照组相比较,差异有统计学意义（P＜0.05）;两组患者术后随访结果显示,观察组3、6及12个月的Qmax、IPSS、QOL及PSA与对照组相比较,差异均无统计学意义（P＞0.05）.结论 小功率钬激光前列腺剜除术与经尿道前列腺电切术用于治疗良性前列腺增生疗效相当,且具有并发症发生率低的优点,值得在临床上推广应用.

Objective To investigate the clinical value of low power holmium laser enucleation in the treatment of prostate for benign prostatic hyperplasia.Methods A total of 312 patients with benign prostatic hyperplasia in our hospital between January 2012 to June 2015 were randomly divided into two groups：patients in the observation group （n =156） received low power holmium laser enucleation,while in the control group （n =156） received transurethral resection of prostate.The operation time,removal weight of proliferation,postoperative serum Na＋,blood Hb,complications,catheter indwelling time,hospital stays and postoperative maximum urinary flow rate （Qmax）,International Prostate Symptom Score （IPSS）,quality of life score （QOL）,and serum prostate-specific antigen （PSA） were compared between the two groups.Results The removal weight of proliferation,postoperative serum Na＋,blood Hb,washing time after operation,complications,and hospital stays between the two groups were statistically significant （P ＜ 0.05）.The Qmax,IPSS,QOL and PSA at 3,6 and 12 months after operation between the two groups were no statistical differences （P ＜ 0.05）.Conclusions Low power holmium laser enucleation in the treatment of benign prostatic hyperplasia has similar efficacy with transurethral resection of prostate,and the former has the advantage of lower complication rate,so it is worthy of clinical application.