局部进展期胰腺癌的放化疗进展

Advances in chemotherapy and/or radiotherapy of locally advanced pancreatic cancer

胰腺癌是常见的消化系恶性肿瘤,随着社会的发展及生活的改善,其发病率亦上升,2012年Globocan估计胰腺癌患者在中国占所有诊断的19.45%,其中每年约新增337900人罹患胰腺癌,并约有330400人死于胰腺癌.由于临床上在早期无特异性症状和体征,确诊时已转移,致其预后很差及死亡率较高.目前胰腺癌的治疗仍是医学界的一大挑战,手术、化疗及放疗是治疗胰腺癌的方法.本文主要讲述放疗及化疗在局部进展期胰腺癌治疗的进展.

Pancreatic cancer is a common malignant tumor of the digestive system with very poor prognosis and high mortality, and its incidence shows a rising trend. According to the 2012 Globocan estimates, there were -337900 newly diagnosed pancreatic cancer cases in China each year, accounting for 19.45% of all new case in the world, and about 330400 people died of this malignancy. Due to the absence of specific symptoms and signs in the early stage, the early diagnosis is difficult. At present, the treatment of pancreatic cancer remains a major challenge in the medical community. Surgery, chemotherapy, and radiotherapy are the treatment options for pancreatic cancer. This article focuses on the progress in the chemotherapy and/or radiotherapy of locally advanced pancreatic cancer.