MS Coat脱敏剂与多乐氟治疗牙周翻瓣术后牙本质敏感的疗效观察

目的比较MS Coat脱敏剂与多乐氟氟化钠护齿剂治疗牙周翻瓣术后根面牙本质敏感的疗效。方法选取因中晚期牙周炎行牙周翻辩术2周后根面牙本质敏感症患者，随机分为MSCoat脱敏组、多乐氟组、空白对照组在统一标准下根据敏感程度变化进行即刻、1个月、3个月疗效对照分析。采用因正畸需要拔除的离体牙构建牙本质敏感模型，根据扫描电镜（SEM）测量的牙本质小管口直径和密度，小管内封闭剂渗入量对比脱敏效果。结果MS Coat脱敏剂、多乐氟氟化钠护齿剂即刻均有脱敏效果（P〈0．05），多乐氟即刻疗效优于MS Coat脱敏剂（P〈0．05）；1、3个月时MSCoat脱敏剂仍有脱敏效果，且优于多乐氟氟化钠护齿剂（P〈0．05），多乐氟于1、3个月后疗效与空白组比较差异无统计学意义（P〉0．05）。离体牙SEM结果显示：MS Coat脱敏剂和多乐氟氟化钠护齿剂脱敏后均会即刻减少牙本质小管口的密度与直径，渗入封闭牙本质小管（P〈0．05）；且与MS Coat脱敏剂比较，多乐氟氟化钠护齿剂脱敏后牙本质小管口的密度与直径减少量更多（P〈0．05）。结论MS Coat脱敏剂和多乐氟对翻瓣术后根面牙本质敏感均有脱敏效果，多乐氟即刻脱敏效果较佳，而MS Coat脱敏剂的脱敏效果更长期稳定。

Objective To observe and evaluate the efficacy of MS Coat desensitizer and Duraphat sodium fluoride on postoperative root dentin hypersensitivity after Flap surgery. Methods 1. Patients with root dentin hypersensitivity after flap surgery because of medium or severe periodontitis were selected and then randomly divided the teeth into three groups： blank control group, MS Coat desensitizer group, and Duraphat sodium fluoride group. Desensitization effect was compared immediately, one month and three months after therapy. 2. Teeth extracted from patients were selected for orthodontic treatment, and the sensitive dentin model was constructed. Then they were randomly divided into three groups： blank control group, MS Coat desensitizer group, and Duraphat sodium fluoride group. The three groups were dealt respectively, and cross-sectional density and diameter, length of permeation on dentin tubule were observed by scanning electron microscope. Results In clinical test, both MS Coat desensitizer and Duraphat sodium fluoride showed good desensitizing effect compared with blank control group immediately （ P〈0.05 ） , Duraphat sodium fluoride was more effective （ P〈0.05 ） . After 1 or 3 months, the results showed that MS Coat desensitizer had better efficacy, compared to Duraphat sodium fluoride （ P〈0.05 ） ; and there was no significant difference between Duraphat sodium fluoride group and blank control group （ P〉0.05 ） . The teeth observed by scanning electron microscope showed that both MS Coat desensitizer and Duraphat sodium fluoride would reduce cross-sectional density, diameter and permeate through dentin tubule immediately （P〈0.05） ; and Duraphat sodium fluoride had more reduction in density and diameter, longer permeation （ P〈0.05 ） . Conelusion Both MS Coat desensitizer and Duraphat sodium fluoride can effectively relieve dentin hypersensitivity after flap surgery, Duraphat sodium fluoride is more effective immediately, while MS Coat desensitizer shows more stable and long-term efficacy.