陶瓷膜预处理1,3-丙二醇发酵液

PRETREATMENT OF 1,3-PROPANEDIOL FERMENTED BROTH BYCERAMIC MEMBRANE

使用生物发酵法生产1,3-丙二醇发酵液中重要的一环就是发酵液中菌体的分离与脱除,本文使用陶瓷膜对1,3-丙二醇发酵液的预处理工艺进行初步研究,对不同孔径陶瓷膜进行筛选,并对其过滤条件进行优化。结果表明,10nm陶瓷膜可以明显去除发酵液中的蛋白和菌体等大分子杂质,且具有良好的再生性和可重复性,使用自主研发的清洗剂清洗被膜管污染,其膜通量可恢复为初始膜通量的100%。研究表明,使用陶瓷膜处理1,3-丙二醇发酵液是完全可行的。

Glycerol product 1,3-propanediol fermented broth by biological zymolysis methods, It is important part to remove and separate thalli in the 1,3-propanediol fermented broth. The pretreatment process of 1,3-propanediol fermented broth by ceramic membrane was investigated. Ceramic membrane with various pores were screened, and different operating parameters were optimized. It was shown that ceramic menbrance of 10nm obviously remove protein and thalli, which have good reusability and repeatability. Contaminated ceramic membrane was washed by self-developed cleaning agent , the flux of membrane can be recovered. Study shows that it is entirely feasible to pretreat 1,3-propanediol fermented broth by ceramic membrane..