改良2.5 mm辅助切口MSICS术对白内障患者手术性散光及角膜内皮细胞的影响

Influence of modified auxiliary 2.5 mm incision surgery conbined MSICS surgery to astigmatism and corneal endothelial cells in cataract patients

目的探讨改良2.5 mm辅助切口手法无缝线小切口非超声乳化白内障手术(MSICS)对白内障患者手术性散光及角膜内皮细胞的影响。方法 620例(780只眼)白内障患者依据随机数字表法将患者分为2组:观察组行改良2.5 mm辅助切口MSICS术,对照组行MSICS术,比较两组患者视力、手术形散光值、角膜内皮细胞变化。结果两组患者术后裸眼视力均显著改善(P<0.05),但观察组改善程度优于对照组(P<0.05);两组患者术后散光值均显著降低(P<0.05),但观察组术后1周和2周的散光值显著低于对照组(P<0.05);观察组角膜内皮密度计数损失率和角膜六角形细胞比例下降幅度显著低于对照组(P<0.05);观察组术后不良反应率(15.9%)显著低于对照组(26.8%)(P<0.05)。结论改良2.5 mm辅助切口MSICS术能够有效预防白内障患者术后手术性散光发生,降低角膜内皮损伤,提高视觉质量,是白内障患者手术治疗的另一重要选择。

Objective To investigate the influence of modified auxiliary 2.5 mm incision surgery for cataract surgery in patients MSICS astigmatism and corneal endothelial cells.Methods 620 cases（780 eyes） in accordance with cataract patients randomly were divided into two groups：observation group underwent modified 2.5 mm auxiliary incision sutureless small incision non-phacoemulsification cataract surgery（MSICS） patients in the control group underwent surgery MSICS compared two groups of patients with visual acuity,astigmatism surgery shape values,changes in corneal endothelial cells.Results The postoperative uncorrected visual acuity improved significantly（P〈0.05）,but the degree of improvement in the observation group than the control group（P〈0.05）;postoperative patients with astigmatism values were significantly lower（P〈0.05）,but observation group after 1 week and 2 weeks astigmatism values were significantly lower than the control group（P〈0.05）;the observation group corneal endothelium count density loss rate and corneal hexagonal cell ratio decline was significantly lower than the control group（P〈0.05）;postoperative adverse reaction rates observed（15.9%） was significantly lower than the control group（26.8%）（P〈0.05）.Conclusion The modified2.5 mm auxiliary incision MSICS cataract surgery can be effective in preventing the occurrence of postoperative astigmatism surgery,reduce corneal endothelial damage,improve the visual quality is another important option for patients with cataract surgery