定喘颗粒治疗毛细支气管炎痰热内蕴证的临床研究

Clinical Study of Dingchuan Granule in Treatment of Bronchiolitis Accumulation of Phlegm Heat Syndrome

目的:研究定喘颗粒治疗毛细支气管炎痰热内蕴证的临床效果。方法:选取2015年4月-2017年4月本院收治的120例毛细支气管炎痰热内蕴证患儿,依据治疗方法将其分为单独西医治疗组(对照组)和西医结合定喘颗粒治疗组(观察组),各60例。对两组患儿的主要中医症候积分、临床疗效、不良反应发生情况进行统计分析。结果:观察组的咳嗽、咳痰、哮鸣音积分及总分均显著低于对照组(P<0.05);观察组的治疗总有效率为96.7%(58/60),显著高于对照组的83.3%(50/60)(P<0.05);两组不良反应发生率分别为6.7%(4/60)、3.3%(2/60),比较差异无统计学意义(P>0.05)。结论:定喘颗粒治疗毛细支气管炎痰热内蕴证的临床效果好,值得推广应用。

Objective：To study the clinical effect of Dingchuan Granule in treatment of bronchiolitis accumulation of phlegm heat syndrome.Method：120 children with bronchiolitis accumulation of phlegm heat syndrome in our hospital from April 2015 to April 2017 were selected,according to the treatment methods,they were divided into western medicine alone treatment group（control group） and western medicine combined with Dingchuan Granule group（observation group）,60 cases in each group.The main TCM symptoms integral,clinical efficacy and adverse reactions of two groups were statistically analyzed.Result： The cough,expectoration,wheezing scores and total score of observation group were significantly lower than those of control group（P〈0.05）,the total effective treatment of observation group was 96.7%（58/60）,which was significantly higher than 83.3%（50/60） of control group（P〈0.05）,the incidence of adverse reactions was 6.7%（4/60） and 3.3%（2/60） respectively,but the difference was not statistically significant（P〉0.05）.Conclusion：The clinical effect of Dingchuan Granule in treatment of bronchiolitis accumulation of phlegm heat syndrome is good,it is worthy of popularization and application.