临床药师参与1例头孢哌酮舒巴坦致药物热用药分析

Clinical Pharmacists' Participation in Analysis of 1 Case of Drug Fever Induced by Cefoperazone Sulbactam

目的认识、了解药物热的发生特点、诊断依据及处理方法,以避免发生病情误诊、误治。方法神经内科临床药师对1例应用头孢哌酮舒巴坦后,先出现皮疹后体温异常升高的患者的用药进行分析。结果与结论头孢哌酮舒巴坦引起药物热属机体常见的免疫反应,由于发生较隐匿,易干扰医师正确诊断,延误治疗。临床药师参与药物治疗,可以及时发现药物热的可能性,提高抗菌药物的用药合理水平,避免患者治疗成本的增加,节约医疗资源。

Objective To understand the occurrence characteristics, diagnosis basis and treatment methods of drug fever, so as to avoid misdiagnosis and mistreatment. Methods The clinical pharmacists in the Department of Neurology analyzed the use of cefoperazone sulbactam in 1 patient whose body temperature was abnormally high after first rash. Results and Conclusion Drug fever induced by cefoperazone sulbactam is one of the common immune reactions in the body. Because of its concealment, it is easy to interfere with the doctor＇s correct diagnosis and delay the treatment. Clinical pharmacists participating in drug treatment can discover the possibility of drug fever in time,improve the rational use level of antibiotics,avoid the increase of patient＇s treatment cost and save medical resources.