妊娠期甲状腺功能减退症与妊娠期高血压疾病关系的研究

Research on Correlation between the Pregnancy Hypothyroidism and Pregnancy High Blood Pressure Diseases

目的探讨妊娠期甲状腺功能减退症与妊娠期高血压疾病关系的关系,为临床的治疗与预防提供理论依据。方法随机选取2015年3月—2016年4月在该院治疗的孕妇为研究对象,随机选取甲状腺功能减退的孕妇76例为观察组,甲状腺功能正常的孕妇76例为对照组,研究妊娠期甲状腺功能减退症与妊娠期高血压疾病关系。结果观察组患者游离三碘甲状腺原氨酸、血清游离甲状腺激素水平[(3.32±1.33)、(9.46±4.22)pmol/L]低于对照组[(4.93±1.67)、(18.21±2.65)pmol/L],血清中促甲状腺激素及甲状腺过氧化物酶抗体的含量[(17.01±12.32)、(17.46±8.09)m U/L]高于对照组(1.72±1.89)、(23.69±13.87)m U/L],差异有统计学意义(P<0.01)。结论有效地补充患者甲状腺水平,使得患者甲状腺功能保持正常,改善妊娠期的体质具有重要的意义。

Objective To study the correlation between the pregnancy hypothyroidism and pregnancy high blood pressure diseases thus providing theoretical basis for the clinical treatment and prevention. Methods 152 cases of pregnant women admitted and treated in our hospital from March 2016 to April 2016 were random selected as the research objects and randomly divided into two groups with 76 cases in each, the observation group were the pregnant women with hypothyroidism,while the control group were the pregnant women whose thyroid function was normal, and the correlation between the pregnancy hypothyroidism and pregnancy high blood pressure diseases was researched. Results The free triiodothyronine and serum free thyroid gland hormone levels in the observation group were lower than those in the control group [(3.32 ±1.33)pmol/L,(9.46±4.22)pmol/L vs(4.93±1.67)pmol/L,(18.21 ±2.65)pmol/L], and the contents of thyrotropic hormone and thyroid peroxidase antibody were higher than those in the control group[(17.01±12.32)m U/L,(17.46±8.09)m U/L vs(1.72±1.89)m U/L,(23.69±13.87)m U/L], and the differences were statistically significant(P<0.01). Conclusion Effectively increasing the thyroid level of patients, making the thyroid function of patients normal and improving the body constitution during the pregnancy period are of important significance.