盐酸右美托咪啶对腹腔镜结直肠癌根治术患者麻醉苏醒质量的影响

Effect of Dexmedetomidine Hydrochloride on the Anesthesia Awakening Qua lity of Patients with Laparoscopic Radical Resection of Colorectal Cancer

目的探讨盐酸右美托咪啶对腹腔镜结直肠癌根治术患者麻醉苏醒质量的影响。方法方便选取该院2015年8月—2016年7月接收的行腹腔镜结直肠癌根治术患者90例为研究对象,采用随机数字表法分为对照组与观察组,对照组患者应用0.9%氯化钠注射液静脉输注,观察组患者应用盐酸右美托咪啶,观察并对比两组患者麻醉苏醒质量各指标及并发症发生率。结果观察组术后术后自主呼吸恢复时间(13.24±3.09)min、睁眼时间(18.01±3.03)min及拔管时间(22.07±3.22)min,麻醉指标恢复时间均短于对照组(14.57±3.12)、(19.87±3.33)、(24.65±3.26)min,差异有统计学意义(P<0.05);观察组患者呛咳率及躁动率44.44%、40.00%均少于对照组11.11%及11.11%,差异有统计学意义(P<0.05)。结论腹腔镜结直肠癌根治术患者应用盐酸右美托咪啶的麻醉苏醒质量较高,可作为有效麻醉方案进行推广应用。

Objective To study the effect of dexmedetomidine hydrochloride on the anesthesia awakening quality of patients with laparoscopic radical resection of colorectal cancer. Methods 90 cases of patients with laparoscopic radical resection of colorectal cancer admitted and treated in our hospital from August 2015 to July 2016 were convenient selected as the research objects and randomly divided into two groups, the control group adopted the venous infusion of 0.9% sodium chloride injection, the observation group adopted the dexmedetomidine hydrochloride, and various indexes of anesthesia awakening and incidence rate of complications of the two groups were observed and compared. Results The postoperative autonomous respiration recovery time, eye opening time and tube drawing time in the observation group were shorter than those in the control group, [（13.24 ±3.09）,（18.01 ±3.03）,（22.07 ±3.22）min vs（14.57 ±3.12）,（19.87 ±3.33）,（24.65 ±3.26）min],and the differences were statistically significant（P〈0.05）; the bucking rate and dysphoria rate in the observation group were lower than those in the control group,（44.44%, 40.00% vs 11.11%, 11.11%）, and the differences were statistically significant（P〈0.05）. Conclusion The anesthesia awakening quality of dexmedetomidine hydrochloride in patients with laparoscopic radical resection of colorectal cancer is higher, which can be used as an effective anesthesia plan for promotion and application.