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CD10阴性成人急性淋巴细胞白血病的预后分析 被引量:2

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摘要 目的探讨初诊成人急性淋巴白细胞白血病(ALL)患者骨髓CD10表达,以及与预后的关系。方法回顾性分析连续收治的>14岁的49例ALL患者临床资料。分析CD10抗原阴性表达患者的临床特征与完全缓解率(CR)、复发率的关系。分析总生存时间(OS)和无病生存时间(EFS)有关的危险因素。结果 CD10阴性10例,CR9例,CR率90.0%;阳性39例,CR 37例,CR率94.9%,差异无统计学意义(>0.05)。CD10阳性复发16例,阴性复发8例,差异有统计学意义(<0.05)。CD10阴性患者具有低血小板(血小板计数≤20×109/L)(<0.05)、高白细胞(白细胞计数≥50×109/L)(<0.05)的临床特点。CD10阴性患者EFS、OS更短(均<0.05)。结论 CD10阴性表达的成人急淋具有低血小板、高白细胞的临床特征,可作为判断成人急性淋巴细胞白血病预后不良的危险因素。
机构地区 丽水市中心医院
出处 《现代实用医学》 2017年第10期1319-1321,共3页 Modern Practical Medicine
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