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老年稳定性冠心病伴抑郁患者血小板P2Y12受体水平的研究 被引量:1

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摘要 目的探讨老年稳定性冠心病伴抑郁患者血小板P2Y12受体水平。方法根据情绪状况将120例老年稳定性冠心病患者分为抑郁组与非抑郁组,另选性别、年龄匹配的70例健康人为对照组。采用酶联免疫吸附法测定血浆中血小板P2Y12受体水平。结果抑郁组患者血小板P2Y12受体浓度高于非抑郁组和健康对照组(均<0.05);非抑郁组与健康对照组差异无统计学意义(>0.05)。P2Y12受体水平与HAMD评分无明显关联(>0.05)。结论老年稳定性冠心病伴抑郁患者血小板P2Y12受体水平增高;稳定性冠心病与抑郁的潜在机制仍有待进一步探讨。
机构地区 宁波市第一医院
出处 《现代实用医学》 2017年第10期1323-1324,共2页 Modern Practical Medicine
基金 浙江省自然科学基金(LY14H090003) 浙江省医药卫生科技计划项目(2017KY578) 宁波市自然科学基金(2016A610156)
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