原发性甲状腺淋巴瘤二例分析并文献复习

Report of Two Cases with Primary Thyroid Lymphoma and Literature Review

目的分析原发性甲状腺淋巴瘤的临床表现及诊断经过。方法回顾性分析中国人民解放军第二五一医院收治的2例原发性甲状腺淋巴瘤患者,分析其临床表现及诊断经过。结果 2例患者均为男性,临床表现均为无痛性甲状腺肿大,伴有不同程度的压迫症状。实验室检查无特异性指标,1例病理类型为甲状腺T细胞淋巴瘤,1例病理类型为黏膜相关淋巴组织B细胞淋巴瘤。结论甲状腺结节的鉴别诊断中应特别注意原发性甲状腺淋巴瘤的可能性,尤其是对合并桥本甲状腺炎的患者,更应提高警惕。其确诊需依据病理组织学及免疫组化检查。

Objective To analyze the clinical manifestation and diagnosis of primary thyroid lymphoma. Methods Two cases with primary thyroid lymphoma who were admitted to the 251st Hospital of PLA were retrospectively analyzed. Its clinical manifestation and diagnosis were also analyzed. Results All of the two patients were male, and their clinical manifestations were painless goiter with different degrees of compression symptoms. The laboratory examination of the disease showed no specific indicator. In the study,the pathological types were thyroid T - cell lymphoma and mucosa - associated lymphoid tissue B - cell lymphoma respectively. Conclusion Special attention should be paid to the possibility of primary thyroid lymphoma in the differential diagnosis of thyroid nodules,and the patients combined with hashimoto thyroiditis calls for more vigilance. Diagnosis depends on histopathology and immunohistochemistry examination.