甲基强的松龙治疗重症哮喘并发呼吸衰竭临床效果评价

Clinical effect of methylprednisolone in treating severe asthma and respiratory failure

目的:探讨重症哮喘并呼吸衰竭患者应用甲基强的松龙治疗的效果。方法:选取78例重症哮喘并发呼吸衰竭患者,对其分组比较,分别设定为对照组和观察组,依次采用常规方法和常规方法加甲基强的松龙治疗,每组39例。结果:观察组的治疗总有效率显著高于对照组(P<0.05)。治疗前,两组血气参数对比差异无统计学意义。治疗后,观察组患者的p H、Pa CO2、Pa O2均优于对照组(P<0.05)。结论:甲基强的松龙治疗重症哮喘并发呼吸衰竭,疗效显著,利于患者后期生存质量的提高,故在临床有进一步推广的价值。

Objective：To investigate the effect of methylprednisolone in patients with severe asthma and respiratory failure. Methods： 78 patients with severe asthma complicated with respiratory failure were randomly divided into control group and observation group. Routine method and conventional method were used to treat methylprednisolone in 39 cases. Results： The total effective rate of the treatment group was significantly higher than that of the control group（P〈0.05）. Before treatment, the two groups of blood gas parameters, no statistically significant. After treatment, the levels of p H, Pa CO2 and Pa O2 in the observation group were better than those in the control group（P〈0.05）. Conclusion： Methylprednisolone treatment of severe asthma with respiratory failure, the effect is significant, which is conducive to the improvement of quality of life in patients, so it is worthy of further promotion.