摘要
Chronic kidney disease (CKD) is a worldwide public health problem that is growing in prevalence and is associated with severe complications. During the progression of the disease, a majority of CKD patients suffer oral complications. Dental implants are currently the most reliable and successful treatment for missing teeth. However, due to complications of CKD such as infections, bone lesions, bleeding risks, and altered drug metabolism, dental implant treatment for renal failure patients on dialysis is more challenging. In this review, we have summarized the characteristics of CKD and previous publications regarding dental treatments for renal failure patients. In addition, we discuss our recent research results and clinical experience in order to provide dental implant practitioners with a clinical guideline for dental implant treatment for renal failure patients undergoing hemodialysis.
Chronic kidney disease (CKD) is a worldwide public health problem that is growing in prevalence and is associated with severe complications. During the progression of the disease, a majority of CKD patients suffer oral complications. Dental implants are currently the most reliable and successful treatment for missing teeth. However, due to complications of CKD such as infections, bone lesions, bleeding risks, and altered drug metabolism, dental implant treatment for renal failure patients on dialysis is more challenging. In this review, we have summarized the characteristics of CKD and previous publications regarding dental treatments for renal failure patients. In addition, we discuss our recent research results and clinical experience in order to provide dental implant practitioners with a clinical guideline for dental implant treatment for renal failure patients undergoing hemodialysis.
作者
Yuan,Quan
Xiong,Qiu-Chan
Gupta,Megha
Maria Lopez-Pintor,Rosa
Chen,Xiao-Lei
Seriwatanachai,Dutmanee
Densmore,Michael
Man,Yi
Gong,Ping
Quan Yuan Qiu-Chan Xiong Megha Gupta Rosa Maria Lapez-Pintor Xiao-Lei Chen Dutmanee Seriwatanachai Michael Densmore Yi Man Ping Gong(State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China Department of Oral Implantology, West China Hospital of Stomatology, Sichuan University, Chengdu, China Department of Preventive Dental Sciences, Division of Pedodontics College of Dentistry, AI-Showajra Academic Campus, Jazan University, Gizan, Kingdom of Saudi Arabia DeparLment of Oral Medicine and Surgery, School of Dentistry Complutense University, Madrid, Spain Department of Nephrology, West China Hospital, Sichuan University, Chengdu, China Department of Oral Biology, Faculty of Dentistry Mahidol University, Bangkok, Thailand and 7Department of Oral Medicine, Infection, and Immunity, Harvard School of Dental Medicine, Boston, USA Correspondence: Dr Q Yuan, State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University No. 14, Section 3, Renmin South Road, Chengdu 610041, China)
基金
supported by grants from the National Natural Science Foundation of China(NSFC 81371173)
the State Key Laboratory of Oral Diseases(SKLOD201704)
the International Team for Implantology(Grant No.975_2014,Basel,Switzerland)
the National Key R&D Program of China during the thirteenth Five-Year Plan(2016YFC1102700)