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制作胸水细胞蜡块检测肺腺癌EGFR突变

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摘要 近年来,我国肺癌发病率和病死率呈显著上升趋势,60%-85%肺癌患者发现时已属晚期,无法进行根治性手术切除。表皮生长因子受体(EGFR)基因突变状态已成为晚期肺腺癌指导治疗和判断预后的重要指标,但目前突变特异性扩增系统(ARMS)技术检测肺癌实体瘤EGFR基因突变情况,大部分是在手术活检标本上应用,传统的细胞学制片技术普遍存在不易于观察、阳性检出率低、样本无法长期保存等诸多缺点。
出处 《诊断病理学杂志》 2017年第9期716-717,共2页 Chinese Journal of Diagnostic Pathology
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