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危重病相关皮质类固醇激素不足诊断争议和进展 被引量:4

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摘要 危重病相关皮质类固醇激素不足( critical illness related corticosteroid insufficiency, CIRCI)是指在危重病状态下,下丘脑-垂体-肾上腺轴( hypothalamic-pituitary-adrenal axis,HPA轴)出现功能障碍(肾上腺皮质功能不全),和(或)糖皮质激素抵抗导致皮质类固醇激素绝对或相对数量和(或)活性不足,进而导致机体抗炎效应和维持循环稳态等适应应激能力减弱。
出处 《中华急诊医学杂志》 CAS CSCD 北大核心 2017年第10期1200-1204,共5页 Chinese Journal of Emergency Medicine
基金 国家自然科学基金青年基金(81570017) 浙江省医药卫生科技计划项目(骨干人才A类)(2016RCA014).
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