B超测量11～13孕周胎儿颈项透明层厚度在早孕期胎儿畸形筛查中的价值

The Value of Transparent Layer Thickness of Fetal Neck in 11-13 Pregnancy Week in B super

目的探析B超测量11~13孕周胎儿颈项透明层(NT)厚度在早孕期胎儿畤形筛查中的价值。方法选取553例11~13孕周单胎妊娠孕妇,彩色多普勒超声检查,对胎儿头臂径长度及NT厚度进行测量。结果 350例正常胎儿,孕期发现30例畸形胎儿,异常胎儿中23例NT值≥2.5 mm。正常胎儿的NT值与正太分布相服从,且伴孕周增加而呈现相应增加。当将NT临界值设定2.5 mm时,有较为平衡特异度及灵敏度。结论 11~13孕周乃是对NT实施超声测量的最佳时间,当NT>2.5 mm时,则可将其当作对胎儿崎形实施早期筛查的一个重要指标。

Objective To study the value of ultrasound measurement of fetal neck（NT） thickness in the fetal malformation during early pregnancy in the first trimester of pregnancy（11-13）. Methods In our hospital 553 cases of singleton pregnancy 11-13 weeks of gestation, to systematically observe the anatomical structure of children, and the fetal head and arm length and thickness measurement NT. Results 350 cases of normal fetus during pregnancy, found 30 cases of fetal malformation, fetal abnormalities in 23 cases of NT value is more than 2.5 mm. When the critical value of 2.5 mm is set to NT, there is a balance of specificity and sensitivity. Conclusion 11-13 gestational week is the best time for the implementation of NT ultrasound measurement, when NT〉2.5 mm, it can be used as an important indicator of early screening for fetal malformations.