摘要
zpl (zip-like) gene mutant embryos showed the cuticular defect with alternative denticle rows and a hole from head to abdomen. zpl mutants also caused the overgrowth of neural cells and axons both in CNS and PNS as well as the wrong pathway of neural fasciculation and the disappearance of hypophysis, as shown by whole mount embryos stained withantibody against HRP and MAb-22C10. Genetic analysis has protided evidence that zpl, located in the right arm ofthe second cliromosome (between 75 and 102 genetic map units), is a new gene closely related to the zip gene.
zpl (zip-like) gene mutant embryos showed the cuticular defect with alternative denticle rows and a hole from head to abdomen. zpl mutants also caused the overgrowth of neural cells and axons both in CNS and PNS as well as the wrong pathway of neural fasciculation and the disappearance of hypophysis, as shown by whole mount embryos stained withantibody against HRP and MAb-22C10. Genetic analysis has protided evidence that zpl, located in the right arm ofthe second cliromosome (between 75 and 102 genetic map units), is a new gene closely related to the zip gene.