血清C反应蛋白、白蛋白及其比值在炎症相关性疾病中的进展

Current Status and Progress of Serum C-reactive Protein,Albumin and Its Ratio in Inflammatory Related Diseases

血清C反应蛋白(CRP)作为一种常用的炎症指标,目前被广泛应用于临床炎症反应相关性疾病的诊断及评估。血清白蛋白(ALB)作为临床生化检测的重要项目,通常被直接用来评价患者的营养状态,同时也可间接反映疾病所致机体的消耗程度,而炎症相关性疾病患者大多存在急慢性消耗。目前,关于CRP、ALB及其比值的研究多集中于急性呼吸窘迫综合征、炎症性肠病、急性肾损伤、急性心肌梗死、恶性肿瘤、感染性疾病、急性主动脉夹层等方面,且研究结果均表明三者与此类疾病的预后相关,可以作为疾病预后的有效预测因子。

Serum C-reactive protein（CRP） is a common inflammatory index,which has been widely used in clinical diagnosis and evaluation of inflammation related diseases.Serum albumin（ALB） as an important item of the clinical and biochemical detection,is usually used to directly evaluate the nutrition status of patients,which can also indirectly reflect the body consumption by diseases,and patients with inflammatory related diseases of have acute and chronic consumption.At present,the research on CRP,ALB and the ratio of the two is mostly focused on acute respiratory distress syndrome,inflammatory bowel disease,acute kidney injury,acute myocardial infarction,malignant tumor,infectious diseases,acute aortic dissection and so on,and the results showed that the three are related to the prognosis,therefore can be used as effective predictors.