禽类肠道主要APUD细胞分布及其生理功能的研究进展

Research Progress on Distribution and Physiologic Functions of Major Amine Precursor Uptake and Decarboxylation Cells in Gut of Avian

禽类动物肠道中存在许多能够分泌肽类激素的内分泌细胞(Amine Precursor Uptake and Decarboxylation Cells,APUD细胞),主要包括S细胞、G细胞、D细胞、PP细胞、I细胞、L细胞、N细胞、M细胞、K细胞,它们分别释放肠促胰液素、胃泌素和脑啡肽、生长抑素和血管活性肠肽、禽胰多肽、缩胆囊素、肠高血糖素、神经降压素、胃动素、葡萄糖依赖性促胰岛素多肽等相关激素,在禽类动物肠道的营养、消化吸收和免疫功能等方面发挥着重要的作用.对禽类肠道主要APUD细胞的种类、分布及生理功能的研究概况进行综述,为深入研究禽类肠道的生理功能提供参考.

Many diverse APUD cells （ Amine Precursor Uptake and Decarboxylation Cells ） of which secretions are peptide hormones distribute the guts of avian, including S cells, G cells, D cells, PP cells, I cells, L cells, N cells, M cells, K cells whose secretion respectively is Secretin （SCT）, Gastrin （GAS） and Enkephalin （ENK）, Somatostatin （SS） and Vasoactive Intestinal Peptide （VIP）, Avian Pancreatic Polypeptide （APP）, Choleeystokinin （CCK）, Enteroglucagon, Neurotensin （NT） , Motilin （MOT） , Glucose - denpendent insulinotropic polypeptide （GIP）. They are critically vital to nutrition, digestive absorption and immunization of avian. This review summarizes the studies on categories, distribution and physiologic funtions of chief APUD Cells in the gut of avian for the further deeply researches.