摘要
理解肠道微生态和代谢的改变,鉴定可靠的标志物对结直肠癌早期筛查和早期诊断至关重要。近期的研究发现,肠道菌群及其代谢产物形成的多样化和复杂的肠道生态环境深刻地影响肠内稳态和疾病状态。本文主要介绍了结直肠癌患者肠道菌群及其代谢产物的研究,并集中评述了它们用于癌症早期诊断的最新进展。
Understanding of intestinal micro-ecological and metabolic changes, identification of reliable markers of early colorectal cancer screening and early diagnosis is essential. Recent studies have found that gut microbiota and its metabolites formed a variety of complex intestinal ecological environment which profoundly affect the intestinal stability and disease state. This review focuses on the study of gut microbiota and its metabolites in colorectal cancer patients, and reviews the recent progress of then for the early diagnosis of cancer.
出处
《中华结直肠疾病电子杂志》
2017年第5期421-426,共6页
Chinese Journal of Colorectal Diseases(Electronic Edition)
基金
国家自然科学基金(No.81230057
No.81472262
No.81302066)
上海新兴前沿技术联合攻关项目(No.SHDC 12012106)
关键词
结直肠肿瘤
代谢
肠道菌群
研究进展
Colorectal neoplasms
Metabolism
Gut microbiota
Study progress
