离体与在体血液流变性对比分析

Comparative analysis of hemorheology property of blood in vitro and in vivo

阐明离体与在体血液流变性的意义,揭示两者的可比性。研究着重阐明了3个方面的问题:其一,内摩擦力对血液流变性的影响,离体血高、中、低剪变率黏度和红细胞刚性指数、聚集指数的内涵;其二,管径大于2 mm和小于2 mm两部分动脉中的血液流变性;其三,在体血液流变性与离体血检测指标无可比性。由此得出结论,借助以往那些离体血液流变性指标来判断在体血液流变性是不合适的。

We expound the hemorheological property of blood in vitro and in vivo, and reveal the comparability between them by theoretical analysis. The review mainly focuses on the influence of internal friction on blood flow and the connotation of 3 indexes of blood（high, medium and low shear rate blood viscosity in vitro, erythrocyte rigidity index and erythrocyte aggregation index）. The hemorheological properties of arteries with a diameter greater than 2 mm or less than 2 mm were also discussed in the review, and a theoretical analysis was performed to reveal that there is no comparability between the blood rheology in vivo and the indexes of in vitro blood test. Based on the results, a conclusion is drawn that it is not appropriate to determine the rheological properties of blood in vivo by those hemorheological properties of blood in vitro.