2015年盐城市美沙酮维持治疗患者多药物滥用情况

Multi-drug abuse among methadone maintenance treatment patients of Yancheng City in 2015

目的了解美沙酮维持治疗患者在治疗前后的多药滥用情况,为针对性提供干预措施提供科学依据。方法对盐城市美沙酮维持治疗门诊患者服药前后多药滥用情况进行问卷调查,并对结果进行分析。结果 95例患者参加维持治疗前后多药物滥用人数分别为94人(98.95%)和46人(48.42%),差异有统计学意义(χ~2=62.54,P<0.01);使用药物种类、注射吸毒人数、使用频次、所花费用均有明显下降,有12种成瘾药物在维持治疗前后的使用比例有统计学意义(P<0.05)。logistic回归分析显示,维持治疗前合用冰毒、K粉、摇头丸和治疗后合用地芬诺酯与年龄呈负相关,吸毒年限对维持治疗前合用冰毒及治疗后合用曲马多的影响有统计学意义。结论美沙酮维持治疗对降低多药物滥用有一定的作用,同时仍需进一步加强综合干预,降低药物滥用的危害。

[Objective] To understand the conditions of multi-drug abuse among methadone maintenance treatment patients before and after treatment, provide scientific evidence for the development of targeted prevention and control measures.[Methods]The questionnaire was used to investigate the multi-drug abuse among methadone maintenance treatment patients before and after treatment in Yancheng City,and the results were analyzed. [Results] Among 95 methadone maintenance treatment patients,94（98.95%）and 46（48.42%）was respectively found for multi-drug abuse before and after the treatment,and the difference was statistically significant（χ~2=62.54,P〈0.01）. The drug types,member of injecting drug users,use frequency and cost distinctly reduced after the treatment,and the difference in proportion of 12 addictive drugs abuse was statistically significant between before and after the treatment（P〈0.05）. Logistic regression analysis showed that age was negatively correlated with abuse of methamphetamine,ketamien and ecstasy before treatment,and abuse of diphenoxylate after treatment,and the years of drug abuse had significant influence on abuse of methamphetamine before treatment and abuse of tramadol after treatment.[Conclusion]Methadone maintenance treatment could reduce some hazards of multi-drug abuse. However,it is necessary to strengthen the comprehensive intervention measures to reduce the hazards of drug abuse.