宁河区高危人群梅毒螺旋体抗体检测结果分析

Analysis of test results of the treponema pallidum antibody in high-risk groups in the Ninghe District

目的回顾性分析宁河区梅毒螺旋体抗体阳性检出率及分布特征。方法采用酶联免疫吸附试验(ELISA)、快速血浆反应素环状卡片试验(RPR)、梅毒螺旋体明胶颗粒凝集试验(TPPA)检测不同人群的梅毒阳性率。结果 2012-2016年宁河区梅毒抗体阳性检出率逐年减少,分别为5.88%、4.68%、3.91%、3.46%、2.31%,差异有统计学意义(P<0.05)。男性梅毒抗体阳性检出率为2.87%(114例),低于女性的6.87%(64例),差异有统计学意义(P<0.05)。2012-2016年梅毒抗体阳性检测者男女比逐年升高,分别为1.40∶1、1.70∶1、1.91∶1、1.88∶1、2.08∶1,差异有统计学意义(P<0.05)。吸毒人群、桑拿洗浴中心服务人员、男男同性恋(MSM)、外来务工人员、自愿咨询人员梅毒阳性率分别为2.29%、0.76%、0.31%、0.20%、0.08%,差异有统计学意义(P<0.05)。结论应进一步对宁河区高危人群、普通人群进行性病防治知识的宣传教育,加强综合监测和干预工作,控制梅毒流行,阻断母婴传播。

Objective To retrospective analyse the positive detection rate and distribution characteristics of the treponema pallidum antibody in high-risk groups in the Ninghe District. Methods Using enzyme-linked immunosorbent assay（ELISA）, rapid plasma reagin ring card test（RPR） and treponema pallidum gelatin particle agglutination test（TPPA） to test the syphilis positive rate of different people. Results The syphilis antibody positive detection rate in the Ninghe Disrict reduced year by year from 2012 to 2016 with 5.88%, 4.68%, 3.91%, 3.46%, 2.31%, the difference was statistically significant（P〈0.05）. The syphilis antibody positive detection proportion of male was 2.87%（114 cases）, which was lower than that of female with 6.87%（64 cases）, the difference was statistically significant（P〈0.05）. The proportion of men and women who tested positive for syphilis increased year by year from 2012 to 2016 with 1.40∶1, 1.70∶1, 1.91∶1, 1.88∶1,2.08∶1, the difference was statistically significant（P〈0.05）. The syphilis positive rate of drug users, sauna bath center service personnel, MSM, migrant workers, the voluntary counselling staff were 2.29%, 0.76%,0.31%, 0.20%, 0.31%, the difference was statistically significant（P〈0.05）. Conclusion We should further publicize and educate STD prevention and control knowledge among high-risk groups and ordinary people in Ninghe District, strengthen the comprehensive monitoring and intervention work, control syphilis epidemic, block mother-to-child transmission.