高度近视患者ICL及Artisan PIOL植入后生存质量研究

A survey of the quality of life in high myopia in implantable Collamer lens and Artisan PIOL recipients

目的比较可植入眼内接触镜（Implantable collamer lens，ICL）与前房虹膜固定型有晶状体眼人工晶状体（Phakic intraocular lens，Artisan PIOL）植入对高度近视患者生存质量（Quality of life，QOL）的影响。方法回顾性病例研究。收集2009年1月至2014年10月在广东省人民医院眼科接受ICL（17例34只眼）和前房型Artisan PIOL植入（15例30只眼）的高度近视患者，术后3个月开始，用屈光矫正者生命质量量表（quality of life impact of refractive correction，QIRC）对两组患者QOL进行评估，该表共20个条目，以评分的方式对患者术后的QOL进行评价和对比研究。采用SPSS13．0统计学软件对数据进行统计学分析，独立样本t检验用于比较ICL组与Artisan PIOL组QIRC量表总分、各条目得分，以及不同矫正方法间得分的差异。结果ICL组与Artisan PIOL组术前平均年龄分别为（27．59±6．07）岁、（26．87±4．84）岁；术前平均球镜分别为（-11．07±1．91）D、（-11．51±2．12）D，两组间差异无统计学意义（P=0．715、0．383）。术后QIRC总分ICL组为47．98±3．60，Artisan PIOL组为43．54±2．87，差异有统计学意义（P=0．001）；条目2、12、20评分ICL组优于Artisan PIOL组，差异有统计学意义（P=0．010、0．043、0．002）。结论有晶状体眼人工晶状体植入后明显改善高度近视患者与视觉有关的QOL，ICL植入术后QOL优于Artisan PIOL植入术后。

Objective To compare vision-related quality of life （QOL） in implantable Collamer lens （ICL） recipients and Artisan iris-fixed Phakic intraocular lens （Artisan PIOL） recipients in high myopia. Methods Retrospective study. There were ICL patients 17 cases （34 eyes）, and Artisan PI- OL patients 15 cases （30 eyes）.in Department of Ophthalmology, Guangdong General Hospital. QOL was measured with quality of life impact of refractive correction （QIRC） in consecutive patients at 3 months after ICL or Artisan PIOL implantation in high myopia. Independent-sample t tests （version 13.00, SPSS, Inc.） were used for statistical comparison of overall QIRC scores and in an explorato- ry analysis of scores for individual questionnaire items between ICL group and Artisan PIOL group.Results Before surgery, the average age （27.594-6.07 vs 26.87±4.84）, spherical equivalent （-11.07± h91D vs-lh51±2.11D） were similar in ICL recipients and Artisan PIOL respectively （P =0.715, 0.383）. QIRC scores were significantly higher （P =0.001） in ICL recipients （47.984-3.60） than in Arti- san PIOL （43.54±2.87）. The score of item 2, 12, 20 in ICL recipients were significant difference than in Artisan PIOL （P =0.010, 0.043, 0.002）. Conclusions ICL implantation may offer significant QOL advantages over Artisan PIOL in patients with high myopia.